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Identification of target sites in the VHR (DUSP3) enzyme unlocking potential avenues for future sepsis treatment

Jiaqian Wu1, Lutz Tautz1

  • 1Cancer Metabolism and Microenvironment Program, NCI-Designated Cancer Center & Center for Therapeutics Discovery, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, USA.

Expert Opinion on Therapeutic Targets
|November 1, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
DUSP3VHRallosteric modulationdual-specificity phosphatasefragment-based drug discoveryinnate immunitymacrophage signalingprotein tyrosine phosphataseproteolysis-targeting chimerasseptic shock

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