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  6. Integrating Comprehensive Care In The Management Of Sickle Cell Disease Patients In Nigeria

Integrating comprehensive care in the management of sickle cell disease patients in Nigeria

Efobi Chilota Chibuife1, Nri-Ezedi Chisom Adaobi2, Chilaka Ugochinyere Jenny1

  • 1Nnamdi Azikiwe University, Department of Haematology and Blood Transfusion, Ituku-Ozalla Enugu, Nigeria.

Hematology, Transfusion and Cell Therapy
|November 1, 2025

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Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
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View abstract on PubMed

Summary
This summary is machine-generated.

Physicians in Nigeria implement comprehensive sickle cell disease care variably, with key components mainly in urban hospitals. Strengthening care requires equitable workforce distribution and integrating services like neonatal screening.

Area of Science:

  • Hematology
  • Public Health
  • Clinical Practice

Background:

  • Comprehensive sickle cell care involves a multidisciplinary approach from birth to adulthood, including screening, investigations, medications, and referrals.
  • Established by the US Sickle Cell Control Act (1972) and ASH initiatives, its adoption in Nigeria is evaluated.
  • This study assesses the implementation of these strategies by Nigerian physicians.

Purpose of the Study:

  • To examine the extent of comprehensive care strategy implementation in sickle cell disease management.
  • Focus on adult and pediatric hematologists in Nigeria.

Main Methods:

  • Cross-sectional study conducted from September to November 2022 in six tertiary hospitals.
  • Utilized an adapted primary care assessment tool to collect data on physician demographics and care components.
Keywords:
Comprehensive careHaematologistsPaediatriciansRoutine referrals

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  • Data analyzed using descriptive statistics and chi-square tests.
  • Main Results:

    • 157 doctors participated, primarily in tertiary hospitals.
    • Folic acid and proguanil hydrochloride were common; hydroxyurea use was below 50%.
    • Complete blood count was the most frequent investigation; 58% scheduled routine investigations. Adult hematologists ordered more echocardiograms, pediatric hematologists more transcranial Dopplers. Adult hematologists had higher inter-speciality referral rates (p=0.0001). All participants provided counseling on clinic attendance, medication adherence, and lifestyle.

    Conclusions:

    • Key components of comprehensive sickle cell care are practiced at varying levels, predominantly in urban/tertiary hospitals.
    • Policy recommendations include prioritizing equitable workforce distribution and integrating services like neonatal screening and novel therapies for nationwide improvement.
    • Enhancing comprehensive care delivery necessitates addressing disparities in healthcare access and resources.
    Sickle cell disease