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First trimester scan in twins.

Sofia Albuquerque Brás1, Leonor Ferreira1

  • 1Center of Fetal Medicine and Surgery, ULS São José, Rua Viriato 1, 1050-206, Lisbon, Portugal.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|November 1, 2025
PubMed
Summary
This summary is machine-generated.

The first trimester ultrasound is crucial for more than just aneuploidy screening. This early pregnancy scan assesses fetal number, chorionicity, gestational age, major anomalies, and pre-eclampsia risk.

Keywords:
AneuploidiesFetal malformationsFirst pregnancy trimesterScreeningTwin pregnancy

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Area of Science:

  • Maternal-fetal medicine
  • Diagnostic imaging
  • Obstetrics

Background:

  • The first trimester ultrasound, typically performed between 11 and 14 weeks of gestation, is a cornerstone of modern prenatal care.
  • Its utility extends beyond initial screening for chromosomal abnormalities.

Purpose of the Study:

  • To highlight the multifaceted role of the first trimester ultrasound.
  • To detail its applications in twin pregnancies, gestational age determination, anomaly detection, and pre-eclampsia risk assessment.

Main Methods:

  • Utilizing ultrasound technology between 11 weeks 0 days and 13 weeks 6 days of gestation.
  • Comprehensive fetal and maternal assessment including biometric measurements and Doppler evaluation of uterine arteries.

Main Results:

  • The scan accurately determines fetal number, chorionicity, and amnionicity in multiple gestations.
  • It reliably establishes gestational age and detects significant fetal structural abnormalities.
  • Uterine artery evaluation provides insights into pre-eclampsia risk.

Conclusions:

  • The first trimester ultrasound is essential for comprehensive prenatal assessment, not limited to aneuploidy screening.
  • It provides critical information for managing twin pregnancies and predicting pregnancy complications like pre-eclampsia.
  • This early scan optimizes early detection and management of fetal and maternal conditions.