Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperthermophilic Bacteria01:21

Hyperthermophilic Bacteria

469
Domain Bacteria includes some unique hyperthermophilic species. They exhibit remarkable adaptations that enable survival in extreme environments.Thermotoga species are rod-shaped, gram-negative, non-sporulating hyperthermophiles that form a sheath-like envelope called a toga. They ferment sugars or starch, producing lactate, acetate, CO₂, and H₂, and can also grow via anaerobic respiration using H₂ and ferric iron. Found in hot springs and hydrothermal vents, over 20% of their...
469
Diversity of Archaea IV01:29

Diversity of Archaea IV

393
Hyperthermophilic archaea are a group of extremophiles thriving at temperatures above 80°C, often in hydrothermal vents and volcanic soils where conditions surpass the boiling point of water. At such temperatures, proteins, membranes, and DNA in most organisms degrade, but hyperthermophiles have evolved remarkable adaptations to maintain stability and function.Unique Cellular FeaturesHyperthermophilic membranes are composed of a monolayer of biphytanyl tetraether lipids, which resist...
393
Anoxygenic Phototrophic Bacteria01:28

Anoxygenic Phototrophic Bacteria

762
Anoxygenic phototrophic bacteria are a diverse group of microorganisms that perform photosynthesis without producing oxygen. They primarily include purple sulfur bacteria, purple nonsulfur bacteria, green sulfur bacteria, and green nonsulfur bacteria. These bacteria are classified into the Gammaproteobacteria, Alphaproteobacteria, Betaproteobacteria, Chlorobi, and Chloroflexi lineages, each with distinct physiological and ecological adaptations.Purple sulfur bacteria belong to the...
762
Diversity of Archaea I01:30

Diversity of Archaea I

528
Archaea, a domain of single-celled microorganisms, are classified into five major phyla based on genetic and biochemical characteristics: Euryarchaeota, Crenarchaeota, Thaumarchaeota, Korarchaeota, and Nanoarchaeota. Among these, the phylum Euryarchaeota is notable for its remarkable diversity in morphology, metabolism, and ecological adaptations.Morphological and Metabolic DiversityMembers of Euryarchaeota exhibit a variety of cellular shapes, including rods and cocci. Their metabolic pathways...
528
Lipid Catabolism01:25

Lipid Catabolism

838
Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...
838
Biosynthesis in Bacteria01:24

Biosynthesis in Bacteria

546
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
546

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characteristics and Outcomes of Adolescents (15-18 Years) with Chronic Myelogenous Leukemia (CML) in Chronic Phase: The Experience of the International Registry of Childhood CML.

Cancers·2026
Same author

Effect of PHA on viability and stress resilience in Rhodospirillum rubrum.

Journal of applied microbiology·2026
Same author

Reaching Increased Hydrogel Stability <i>In Vivo</i> through β-Hairpin Peptide-Based Hydrogels.

Biomacromolecules·2026
Same author

Three novel Rothia species associated with Antarctic birds harbour novel biosynthetic gene clusters.

FEMS microbiology ecology·2026
Same author

Dynamics and charge transport in PVDF-HFP/protic ionic liquid (PIL) membranes: The effect of PIL concentration.

The Journal of chemical physics·2026
Same author

Refining busulfan exposure enhances pediatric ALL HSCT outcomes: insights from the International FORUM study.

Blood advances·2026

Related Experiment Video

Updated: Jan 12, 2026

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste
08:14

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste

Published on: July 18, 2025

1.0K

Tracking polyhydroxyalkanoate biosynthesis in thermophilic microorganisms.

Brendan Schroyen1, Radwa Moanis2, Hannelore Geeraert3

  • 1Research Group of Microbiology, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium.

International Journal of Biological Macromolecules
|November 1, 2025
PubMed
Summary

Polyhydroxyalkanoates (PHAs) are bioplastics. This study found PHA production is rare in extreme heat-loving microbes, despite some having the necessary genes. Further research is needed to understand this scarcity.

Keywords:
BioinformaticsPhaCPolyhydroxyalkanoatesThermophilesThermus thermophilus

More Related Videos

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
20:28

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

Published on: October 2, 2012

14.6K
Isolation, Propagation, and Identification of Bacterial Species with Hydrocarbon Metabolizing Properties from Aquatic Habitats
10:03

Isolation, Propagation, and Identification of Bacterial Species with Hydrocarbon Metabolizing Properties from Aquatic Habitats

Published on: December 7, 2021

5.2K

Related Experiment Videos

Last Updated: Jan 12, 2026

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste
08:14

Scalable Step-by-Step Approach of Sustainable Bioplastic Production from Food Waste

Published on: July 18, 2025

1.0K
A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
20:28

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

Published on: October 2, 2012

14.6K
Isolation, Propagation, and Identification of Bacterial Species with Hydrocarbon Metabolizing Properties from Aquatic Habitats
10:03

Isolation, Propagation, and Identification of Bacterial Species with Hydrocarbon Metabolizing Properties from Aquatic Habitats

Published on: December 7, 2021

5.2K

Area of Science:

  • Microbiology
  • Biotechnology
  • Genomics

Background:

  • Polyhydroxyalkanoates (PHAs) are microbial biopolyesters with industrial potential.
  • While PHA-related genes are widespread, PHA production in extreme thermophiles is poorly documented.
  • Thermophilic microorganisms offer opportunities for Next-Generation Industrial Biotechnology.

Purpose of the Study:

  • To investigate the prevalence of PHA production in extreme and moderate thermophiles.
  • To identify potential thermophilic PHA-producing microorganisms using bioinformatics.
  • To address the research gap concerning PHA biosynthesis in extreme thermal environments.

Main Methods:

  • Developed a bioinformatics pipeline to screen thermophilic genomes for PHA synthesis genes (PhaC).
  • Curated and analyzed protein sequences of PHA polymerase (PhaC).
  • Screened bacterial and archaeal genomes, including Thermus thermophilus, using various analytical methods.

Main Results:

  • PhaC genes are common in moderate thermophilic bacteria but absent in extreme thermophilic bacteria.
  • Limited extreme thermophilic archaea (Ferroglobus, Geoglobus, Archaeoglobus) possess putative phaC genes.
  • No PHA production was detected in Thermus thermophilus under tested conditions, contradicting previous reports.

Conclusions:

  • PHA production is scarce in extreme thermophiles and hyperthermophiles.
  • The reasons for the limited PHA production in these organisms require further investigation.
  • This study highlights the need for continued exploration of microbial bioplastic synthesis in diverse environments.