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Lethal Sycamore maple intoxication in a grazing three-month-old foal
N Janzen1, J Sander2, M Terhardt2
1Hannover Medical School, Department of Clinical Chemistry, Carl-Neuberg-Str. 1, Hannover, Lower Saxony, 30625, Germany; Screening-Labor Hannover, Postbox 91 10 09, Hannover, Lower Saxony, 30430, Germany.
Journal of Equine Veterinary Science
|November 1, 2025
Summary
A young foal experienced severe myopathy after ingesting toxic maple tree parts. This highlights the danger of Acer species containing hypoglycin A (HGA) and methylencyclopropylglycine (MCPRG) to horses.
Area of Science:
- Veterinary Toxicology
- Equine Medicine
- Plant Toxicology
Background:
- Maple trees (Acer species) can be toxic to grazing horses.
- Ingestion of certain maple parts can lead to severe health issues in equines.
- Atypical myopathy is a serious condition affecting horses.

