Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

906
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
906
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

817
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
817
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.2K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

399
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
399
Stages of Infection01:26

Stages of Infection

64.8K
Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
64.8K
Chronic Pharyngitis01:23

Chronic Pharyngitis

10.8K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
10.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Defence Engagement (Health) between the UK and Ireland since the Good Friday Agreement in 1998.

BMJ military health·2024
Same author

Assessment of hot flushes and vaginal dryness among obese women undergoing bariatric surgery.

Climacteric : the journal of the International Menopause Society·2015
Same author

Occult vs. overt upper gastrointestinal bleeding - inverse relationship and the use of mucosal damaging and protective drugs.

Alimentary pharmacology & therapeutics·2015
Same author

Influence of foliar glucosinolates in oilseed rape and mustard on feeding and growth of the bertha armyworm,Mamestra configurata Walker.

Journal of chemical ecology·2013
Same author

A national survey of independent living donor advocates: the need for practice guidelines.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2012
Same author

Clinical trial: the incidence and early mortality after peptic ulcer perforation, and the use of low-dose aspirin and nonsteroidal anti-inflammatory drugs.

Alimentary pharmacology & therapeutics·2008

Related Experiment Video

Updated: Jan 12, 2026

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
09:45

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering

Published on: January 24, 2025

6.7K

Syphilis in the post-Covid-19 pandemic world.

M R Salvaggio1, C McCloskey2, E Siegrist3

  • 1The University of Oklahoma Health Campus, Department of Internal Medicine, 800 Stanton L Young Blvd, Ste 7300, Oklahoma City, OK 73104, USA.

The American Journal of the Medical Sciences
|November 1, 2025
PubMed
Summary

Syphilis is a persistent clinical concern, with rising cases, particularly congenital syphilis, necessitating increased clinician awareness. Diagnosis and treatment monitoring rely on nuanced testing, and penicillin is the primary therapy, with new options anticipated.

Keywords:
Infectious diseaseReviewSyphilis

More Related Videos

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.8K
Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
08:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

3.2K

Related Experiment Videos

Last Updated: Jan 12, 2026

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
09:45

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering

Published on: January 24, 2025

6.7K
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.8K
Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
08:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

3.2K

Area of Science:

  • Infectious Diseases
  • Public Health
  • Microbiology

Background:

  • Syphilis, caused by *Treponema pallidum*, is an ancient sexually transmitted infection.
  • Recent epidemiological trends show an increase in syphilis incidence, notably congenital syphilis.
  • The diverse clinical presentations of syphilis can challenge diagnosis.

Purpose of the Study:

  • To highlight the continued clinical relevance of syphilis.
  • To emphasize the importance of clinician suspicion given rising case numbers.
  • To discuss current diagnostic and therapeutic strategies for syphilis.

Main Methods:

  • Review of clinical presentations and diagnostic challenges.
  • Evaluation of current serological testing modalities.
  • Assessment of established and emerging treatment guidelines.

Main Results:

  • Syphilis diagnosis requires careful clinical correlation with laboratory findings due to variable test performance.
  • Penicillin remains the gold standard treatment for most stages of syphilis.
  • Emerging therapeutic alternatives are under investigation.

Conclusions:

  • Clinicians must maintain a high index of suspicion for syphilis.
  • Accurate diagnosis and appropriate treatment are crucial for managing syphilis effectively.
  • Ongoing research may expand treatment options for syphilis.