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Updated: Jan 12, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Is age in children with Wilms tumour an important prognostic factor?
Marcin Polok1, Bernarda Kazanowska2, Ewa Bień3
1Department of Pediatric Surgery and Urology, University of Zielona Gora, Ul. Zyty 26, Zielona Gora 65-046, Poland.
Background:
The aim of the study was an assessment of whether the age of patients with WT could be measured as a risk factor and an analysis of the treatment of patients over 10 years old.
Methods:
The data of 942 patients treated because of Wilms tumour from 1997 to 2022 were assessed.
Results:
Patients were divided by age into two groups: group 1 (888 (94,27%) patients age 0-9 years old) and group 2 (54 (5,73%) patients age 10-18 years old). In group 1, there were more patients at higher stage than in group 2 (p<0,05). The histology of low risk in group 1 versus group 2 occurred in 13,4% vs 3,7% patients, of intermediate risk in 66,2% vs 66,7% patients and high risk in 19,9% vs 29,6% patients. Results of treatment were assessed only in group 2 which is a limitation of this study. Overall 62,96% patients survived in this group.
Conclusion:
Wilms tumour in children 10-18 years old is diagnosed at a higher stage and with worse histology. Overall survival in this age group is lower than in younger children, which is in line with the current literature.
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