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Updated: Jul 25, 2026
A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
Published on: January 11, 2018
Quantitative assessment of the temporomandibular joints in patients with osteogenesis imperfecta: a CBCT study
Michelle Briner1, Jean-Marc Retrouvey2,
1University of Missouri-Kansas City, Kansas City, MO, USA.
Objectives:
To evaluate mandibular condylar volume and height in individuals with osteogenesis imperfecta (OI) compared to age- and sex-matched controls using CBCTs.
Study Design:
This study included 48 OI patients and 48 matched controls. CBCTs were analyzed using 3DSlicer and Anatomage-InVivo6 software. Condylar volume and height were measured bilaterally. Data were analyzed using t-tests, ANOVA, and Tukey posthoc tests.
Results:
No sex-based differences in condylar volume were found in either OI or control patients. Volumetric developmental stage differences were significant only in OI patients. In OI patients, condylar height was significantly associated with sex on the right side only. In controls, no sex-based differences were found, but developmental stage differences were significant in the left condyle. No significant differences in volume or height were observed between OI types.
Conclusion:
Individuals with OI, show significantly reduced condylar volume and height, indicating impaired and delayed condylar development consistent with their overall skeletal maturation delay.
