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Related Concept Videos

Sexually Transmitted Infections01:26

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An interactive digital behaviour change intervention to decrease incidence of sexually transmitted infections among

Katie Newby1, Kayleigh Kwah1, Lauren Schumacher1

  • 1Department of Psychology, Sport and Geography, University of Hertfordshire, Hatfield, UK.

Public Health Research (Southampton, England)
|November 3, 2025
PubMed
Summary
This summary is machine-generated.

A web-based intervention called Wrapped may help young people prevent sexually transmitted infections (STIs) by improving condom use. A future trial is feasible, with strategies to ensure diverse participant representation.

Keywords:
ADOLESCENTCONDOM USEDIGITAL HEALTHFEASIBILITY RANDOMISED CONTROLLED TRIALSELF-TESTINGSEXUAL HEALTHSEXUALLY TRANSMITTED INFECTIONSSTIsYOUNG PEOPLEeHEALTH

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Area of Science:

  • Public Health
  • Digital Health Interventions
  • Sexual Health

Background:

  • Sexually transmitted infections (STIs) are common in young people, with potential severe health consequences.
  • Condom use for penetrative sex is inconsistent among youth, despite recommendations.
  • Web-based STI testing services offer limited support for preventing future infections.

Purpose of the Study:

  • To assess the feasibility of conducting a future randomized controlled trial for the 'Wrapped' intervention.
  • To evaluate the potential of 'Wrapped' in supporting correct condom use among young adults.
  • To inform the design of a definitive trial for reducing STI incidence.

Main Methods:

  • A two-arm, parallel-group feasibility randomized controlled trial (RCT) with a nested qualitative study.
  • Recruitment from a web-based STI testing service in five English local authority areas.
  • Intervention group received 'Wrapped' plus usual care; control group received usual care only.

Main Results:

  • 230 participants were randomized; 75.7% returned a valid chlamydia self-sample at 12 months.
  • Estimated 3574 participants needed for a future full trial, based on recruitment and follow-up rates.
  • Participant demographics at 12 months showed some over- and under-representation compared to the sampling pool; no differential attrition by group.

Conclusions:

  • A full-scale randomized controlled trial of the 'Wrapped' intervention is feasible.
  • Sufficient numbers of young people use web-based STI testing to achieve the required sample size for a full trial.
  • Strategies should be implemented to address demographic representation in future studies.