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TMO2 - a novel non-aqueous source of hydrogen peroxide
Fergal P Byrne1, James H Clark1, James Comerford1
1Addible Ltd, Spitfire House 19 Falcon Court, Preston Farm Industrial Estate, Stockton-On-Tees, TS18 3TU, England. james.clark@addible.eu.
None:
Oxidation is a linchpin of the chemical industry, used in the manufacture of ∼60% of all products and intermediates with an associated global value estimated at USD 20-40 billion. Hydrogen peroxide (H2O2) is the preferred green oxidant by virtue of outstanding atom economy and benign co-product (water), yet its routine delivery as dilute aqueous solutions imposes water-compatibility constraints, biphasic mass-transfer penalties, waste generation and costly separations. We report TMO2, a non-aqueous, bench-stable source of H2O2 formed in the green, reusable solvent TMO, decoupling oxidant delivery from water. TMO2 enables peroxide oxidations under homogeneous, organic conditions, obviating phase-transfer operations and reducing waste while avoiding hazardous peracids (Addible Ltd., TMO2 International Patent Application No. PCT/EP2025/074472). Concept, preparation, and representative reactivity are described herein; full procedures and data are provided in the SI.
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