Related Experiment Video
Updated: Jan 12, 2026
Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
Mycoplasma cynos-Associated Canine Infectious Respiratory Disease Complex Pneumonia in 13 Dogs
1VCA Highlands Ranch Animal Specialty and Emergency Center, Highlands Ranch, Colorado, USA.
Objective:
To report the diagnostic results, treatments, and outcomes in 13 dogs with suspected canine infectious respiratory disease complex (CIRDC)-associated pneumonia and Mycoplasma cynos-positive polymerase chain reaction (PCR).
Design:
Retrospective and prospective case series.
Setting:
Emergency and referral hospital.
Animals:
Thirteen client-owned dogs with suspected CIRDC-associated pneumonia and a positive PCR.
Interventions:
None.
Measurements And Main Results:
All dogs with history, clinical signs, and radiographs consistent with CIRDC-associated pneumonia and a positive upper respiratory PCR that presented during a cluster from August 15, 2023, to September 9, 2023, were retrospectively and prospectively included in the series. Among the 13 dogs included, M. cynos was the sole pathogen detected in the airways of eight dogs, while M. cynos and Bordetella bronchiseptica were detected in five dogs. No viral etiologies were detected in this sample. Doxycycline, amoxicillin-clavulanic acid, and fluoroquinolones were frequently prescribed for ≥2 weeks. Follow-up was performed until 1 week after resolution of cough, evidence of radiographic resolution, or death of the dog. Twelve dogs survived, and one was euthanized.
Conclusions:
Mycoplasma cynos was detected as the sole or co-occurring infection during this 3-week period, indicating it may be an important agent in some CIRDC clusters.
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