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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
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Paediatric Oral Lichen Planus
1Department of Oral Medicine, Liverpool University Dental Hospital,University Hospitals of Liverpool Group, UK.
European Journal of Paediatric Dentistry
|November 3, 2025
Summary
Oral Lichen Planus (OLP) in children is uncommon but manageable. This case series highlights that pediatric OLP, while potentially malignant, showed no cancer development in a 2-year follow-up, emphasizing monitoring.
Area of Science:
- Oral Medicine
- Pediatric Dentistry
- Dermatology
Background:
- Lichen Planus is a chronic mucocutaneous disease affecting oral mucosa, skin, and more.
- Oral Lichen Planus (OLP) is less common in children than adults.
- OLP is an oral potentially malignant disorder with a 1% risk of oral cancer.
Purpose of the Study:
- To present a case series of Oral Lichen Planus diagnosed in children.
- To describe the clinical presentation, diagnosis, and management of pediatric OLP.
- To assess the risk of malignant transformation in children with OLP.
Main Methods:
- Retrospective case series of ten pediatric patients diagnosed with OLP.
- Clinical diagnosis alone or confirmed by incisional biopsy.
- Review of patient demographics, clinical presentation, treatment, and follow-up.
Main Results:
- Ten pediatric patients (4 male, 6 female, aged 10-17) diagnosed with OLP.
- Five clinical diagnoses and five histological diagnoses confirmed OLP.
- One case showed moderate dysplasia on an OLP background; no oral cancer developed during a mean 2-year follow-up.
Conclusions:
- Pediatric OLP is rare but can be diagnosed clinically or histologically.
- While OLP carries a risk of malignant transformation, no cases were observed in this pediatric cohort.
- Ongoing monitoring is crucial for early detection of any potential malignant changes in children with OLP.
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