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Cellular profiling identifies targetable T cell phenotypes in lymphocytic variant hypereosinophilic syndrome

Kristy Tefft1, Amy Wang1, Zachary Z Reinstein1

  • 1Department of Dermatology, Northwestern University, Chicago, Illinois, USA.

The Journal of Clinical Investigation
|November 3, 2025
PubMed

With cell-by-cell mapping, we charted immune cells in lymphocytic-variant hypereosinophilic syndrome, found drug targets, and showed targeted therapy removed disease-causing cells and eased symptoms.

Keywords:
DermatologyImmunologyLymphomasMolecular biologyT cells

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