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Macular Hole Closure Between Two Tamponades: A Case Report.
Rituraj P Videkar1, Gangaprasad Amula2, Navneet Mehrotra3
1Vitreoretinal Surgery, Fakeeh University Hospital, Dubai, ARE.
Cureus
|November 3, 2025
Summary
Perfluorocarbon liquid (PFCL) can inadvertently close macular holes during vitreoretinal surgery. Surgeons must ensure complete PFCL removal to prevent potential retinal photoreceptor toxicity and maintain a good prognosis.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Perfluorocarbon liquids (PFCLs) are crucial tools in modern vitreoretinal surgery, enhancing success rates for complex retinal detachments.
- Recent literature highlights PFCL's utility in managing macular holes, with or without concurrent retinal detachment.

