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Updated: Jan 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Co-occurrence of Primary Headache and Tremor in a Young Woman: A Case Report

Koji Hayashi1, Yuka Nakaya1, Mamiko Sato1

  • 1Department of Rehabilitation Medicine, Fukui General Hospital, Fukui, JPN.

Cureus
|November 3, 2025
PubMed

This case report describes a 28-year-old woman presenting with right temporal headache and tremor of the right hand. She had a history of menstrual-related, nonthrobbing headaches but no prior tremors or visual symptoms. Neurological examination revealed a 5-Hz resting and postural tremor in the right upper limb, hyperreflexia, and normal cognitive function, with unremarkable magnetic resonance imaging findings. Blood tests showed euthyroidism and elevated inflammatory and lipid markers. Surface electromyography confirmed the tremor. The patient was diagnosed with tremor associated with primary headache and responded rapidly to clonazepam, with symptom resolution the next day. This case underscores the diagnostic difficulties presented by the atypical co-occurrence of primary headache and tremor. It highlights the importance of considering functional disorders in the differential diagnosis when encountering such presentations, alongside a thorough exclusion of organic causes.

Keywords:
hand tremorheadacheinvoluntary limb movementpositional tremorprimary headache disorderrest tremor

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