IgG-Secreting Lymphoplasmacytic Lymphoma Presenting With Massive Kidney Infiltration

Yuichi Nakamura1, Yoshihiro Itoh1, Tomoyuki Sakamoto1

  • 1Department of Hematology Saitama Medical University Hospital Iruma-gun Saitama Japan.

Clinical Case Reports
|November 3, 2025
PubMed

Various factors related to lymphoplasmacytic lymphoma (LPL) can lead to kidney complications; however, LPL-related kidney complications are not as well-described as those with multiple myeloma. Here, we report a case of IgG-secreting LPL presenting with acute kidney injury owing to direct tumor infiltration. Chemotherapy resulted in hematological and renal improvements.