Embolic Stroke as a Complication of Streptococcus gordonii Prosthetic Valve Endocarditis in a Pacemaker Carrier:

Wassim Hamadeh1, Yasser A Harb2,3, Axam Abdelhadi2,3

  • 1Faculty of Medical Sciences Lebanese University Hadath Lebanon.

Clinical Case Reports
|November 3, 2025
PubMed

In this article, we report the case of a 57-year-old hypertensive man with a prosthetic valve and a pacemaker who presented after many hours of onset of left-sided hemiplegia, left facial drop and dysarthria. Computed tomography of the brain revealed an ischemic stroke, and after an extensive workup the diagnosis of an embolic stroke induced by a Streptococcus gordonii endocarditis was established. This organism is considered to be a rare cause of endocarditis as only a dozen cases were previously reported in the literature. We describe the clinical interventions used, expose the diagnostic approach and challenges faced. To the best of our knowledge, this is the first Streptococcus gordonii-associated endocarditis that is reported in Lebanon and, as such, it widens the geographical setting in which it had been reported and helps gain a better understanding of its epidemiology and strain resistance. Furthermore, it highlights the need to include in the differential diagnosis of endocarditis unusual causative and infectious agents, and as such, it urges clinicians to maintain vigilance towards them and take timely intervention against them in order to ameliorate patients' prognosis. We also provide updates in this article on recent research findings and prevention strategies that may be used in the future against infectious endocarditis.

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