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Synovial Sarcoma; a Rare Entity in Submandibular Gland
Ramaisa Malik Wardah1, Mufaddal Zahra2, Afzal Yumna2
1Department of otolaryngology and head and neck surgery, DOW University of Health and Sciences, Pakistan.
Archives of Razi Institute
|November 3, 2025
Summary
This case report details a rare salivary gland synovial sarcoma in a 48-year-old male. Diagnosis involved histopathology confirming spindle cells positive for CKAE1/AE3, TLE-1, and CD99.
Area of Science:
- Oncology
- Pathology
Background:
- Salivary gland synovial sarcomas are rare oral tumors, <1% of all oral neoplasms.
- These tumors predominantly affect young and adolescent individuals.
- They present diagnostic challenges due to their rarity and varied presentation.

