Successful percutaneous closure of a large ventricular septal defect (VSD) in a 9-month-old Infant: A case report

Ventricular septal defect (VSD) is a common congenital heart defect. In large VSDs with significant left-to-right shunting, percutaneous closure can be an effective alternative to surgical repair. In some cases, percutaneous closure of septal defects is a successful treatment. Our main objective in this case report is to discuss the transcatheter closure of ventricular septal defects in a low-birth-weight infant. We are presenting the case of a 9-month-old male infant who is experiencing failure to thrive (FTT) alongside a significant ventricular septal defect (VSD). The patient successfully underwent percutaneous closure of the VSD using an antegrade approach with a symmetric device. Follow-up evaluations after the procedure confirmed that the closure was effective, the device was in the correct position, and pulmonary hypertension had resolved. As far as we know, this case represents one of the youngest and lowest-weight infants reported in Iran for successful percutaneous VSD closure instead of open surgery.