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Updated: Jan 12, 2026

A Unified Methodological Framework for Vestibular Schwannoma Research
Published on: June 20, 2017
Radiation-induced cavernous malformation within a vestibular schwannoma: A case report
Alex Z Graboyes1, Alexandra E Quimby2, Sabrina Heman-Ackah3
1Department of Otorhinolaryngology - Head & Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.
None:
Cavernous malformations are a well-described complication of intracranial radiation; however, have only once previously been described within a vestibular schwannoma following radiotherapy. We report a case of a 78-year-old woman presenting with new hemifacial spasm 16-years following fractionated radiotherapy for a vestibular schwannoma, with imaging suggesting the formation of a cavernous malformation within the tumor. The patient underwent translabyrinthine resection, with final pathology confirming the diagnosis of a cavernous malformation within the vestibular schwannoma. This case highlights the need to maintain a broad differential in patients with new symptoms following radiotherapy for vestibular schwannomas, including hemifacial spasm. Cavernous malformations should be considered among potential radiation-related complications in patients with vestibular schwannoma. Level of Evidence: IV.

