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Multinodular goiter in ectopic lingual thyroid: a case report with comprehensive review
Dipesh Kumar Yadav1, Noor Fatima1, Maria Aslam1
1Department of Diagnostic Radiology and Imaging, Nishtar Medical University, Multan, Pakistan.
Annals of Medicine and Surgery (2012)
|November 3, 2025
Summary
Multinodular goiter (MNG) in a lingual thyroid is exceptionally rare. Levothyroxine (LT4) therapy effectively reduced mass size and symptoms in a patient who declined surgery, highlighting its utility for this rare ectopic thyroid condition.
Area of Science:
- Endocrinology
- Surgical Pathology
- Medical Imaging
Background:
- Lingual thyroid, a rare ectopic thyroid anomaly, results from failed thyroid descent during embryogenesis, accounting for 90% of ectopic thyroid cases.
- Multinodular goiter (MNG) within a lingual thyroid is exceedingly rare, with only three prior case reports.
- Lingual thyroid can undergo pathological changes similar to orthotopic thyroid tissue, including MNG, influenced by factors like iodine deficiency and genetics.
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