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Updated: Jul 3, 2026

Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
Alginate-based biomaterials in orthopedics: What are the prospects for bacterial alginate?
Andrei A Dudun1,2, Garina A Bonartseva1, Anton P Bonartsev3
1A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russia.
Abstract:
The mini-review explores the potential use of alginates produced biotechnologically by bacteria for the development of various implantable biomaterials intended for bone and cartilage tissue regeneration in orthopedics: the recent studies on the use of algal alginate-based biomaterials in the form of hydrogels, scaffolds, and microparticles for medical applications are considered as a potential opportunity to use bacterial alginate for these applications, taking into account the advantages of biotechnological production of a polymer with desired properties. The methods of producing different alginate-based biomaterials, the manufacturing of implantable medical devices using them, and the surgical techniques for bone and cartilage tissue regeneration using these materials for orthopedic purposes are discussed.
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