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Dimethylsulfoxide-Associated Anaphylaxis in Autologous Stem Cell Transplantation: A Case Report
Didar Yanardag Acik1, Elif Suyani1, Bilal Aygun2
1Department of Internal Medicine and Haematology, Faculty of Medicine, Health Sciences University Adana, Adana, Türkiye.
Case Reports in Medicine
|November 3, 2025
Summary
Dimethylsulfoxide (DMSO) is a common cryoprotectant for hematopoietic stem cells. This report details a rare case of acute anaphylaxis following DMSO administration and its successful management.
Area of Science:
- Hematology
- Immunology
- Pharmacology
Background:
- Dimethylsulfoxide (DMSO) is widely utilized for cryopreservation of hematopoietic stem cells (HSCs).
- While generally considered safe, DMSO can rarely cause adverse reactions, including anaphylaxis.
- Understanding these risks is crucial for patient safety during stem cell transplantation procedures.
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