Related Experiment Video
Updated: May 6, 2026

06:39
Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
10.1K
Dimethylsulfoxide-Associated Anaphylaxis in Autologous Stem Cell Transplantation: A Case Report
Didar Yanardag Acik1, Elif Suyani1, Bilal Aygun2
1Department of Internal Medicine and Haematology, Faculty of Medicine, Health Sciences University Adana, Adana, Türkiye.
Case Reports in Medicine
|November 3, 2025
Abstract:
Dimethylsulfoxide (DMSO) is often used for freezing hematopoietic stem cells. DMSO is associated with mild side effects and rarely serious side effects such as anaphylaxis. We present a patient with acute anaphylaxis after DMSO and patient management.
Related Concept Videos
Allergic Reactions
26.7K
Overview
26.7K
Drug Toxicity: Allergic Reactions
223
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
223
Allergic Reactions: Anaphylaxis
293
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
293

