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Multiple primary malignant neoplasms and long-term survival: A case report
Biao Xie1, Ke Huang1, Shuibo Zhu1
1Department of Thoracic Cardiovascular Surgery, General Hospital of Central Theater Command, Wuhan, Hubei 430070, P.R. China.
Oncology Letters
|November 3, 2025
Summary
This study details a rare case of multiple primary malignant neoplasms (MPMNs), where a patient survived for 38 years with seven distinct cancers. Timely diagnosis and treatment significantly improved survival for this complex oncology case.
Area of Science:
- Oncology
- Clinical Case Studies
Background:
- Morbidity in multiple primary malignant neoplasms (MPMNs) is improving with advancements in tumor diagnosis and treatment.
- MPMNs represent a complex clinical challenge due to the sequential development of distinct primary cancers.

