Related Experiment Video
Updated: Jan 12, 2026

04:40
Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
Published on: November 4, 2022
1.3K
Primary Splenic Follicular Lymphoma Presenting As Isolated Splenomegaly: A Case Report
Pranavi Indukuri1, Steve Thomas2, Pulkit Mehrotra3
1Internal Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|November 3, 2025
Summary
This case study details a rare instance of follicular lymphoma (FL) presenting solely as an enlarged spleen. Splenectomy was crucial for diagnosis and treatment, with rituximab maintaining remission in this indolent B-cell lymphoma.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Follicular lymphoma (FL) is typically characterized by lymph node enlargement.
- Primary splenic involvement without nodal disease is an exceptionally rare presentation of FL.
- Isolated splenomegaly can pose diagnostic challenges in hematologic malignancies.

