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Inhibitors of Virion Maturation and Assembly

Inhibitors of Virion Maturation and Assembly

As part of their replication cycle, certain viruses synthesize long precursor proteins called polyproteins within infected host cells. In human immunodeficiency virus (HIV), two major polyproteins are produced: Gag and Gag-Pol. The Gag polyprotein supplies the structural components of the virus, while Gag-Pol includes essential viral enzymes such as reverse transcriptase, integrase, and protease. After synthesis, these polyproteins move to the host cell membrane, where they assemble into an...

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Related Experiment Video

Updated: Jul 18, 2026

Ex Vivo Infection of Live Tissue with Oncolytic Viruses

Ex Vivo Infection of Live Tissue with Oncolytic Viruses

Published on: June 25, 2011

[Optimizing oncolytic virotherapy with fusogenic envelopes]

Aurianne Pelsma¹, Ngoc Huong Giang Tran², Léa Sabarly²

¹Université Paris Saclay, Gustave Roussy, CNRS UMR 9196, Physiologie et Pathologie moléculaires des rétrovirus endogènes et infectieux, F-94805, Villejuif, France, Viroxis, Villejuif, France.

Virologie (Montrouge, France)

|November 3, 2025

Summary

No abstract available in PubMed .

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