Related Experiment Video
Updated: Jan 12, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
A pharmacist initiative to reduce opioid prescribing in primary care
Simon Gill1, John Bailey2, Sadia Bashir Nafees2
1Wrexham Maelor Hospital, Betsi Cadwaladr University Health Board, Wrexham LL13 7TD, United Kingdom.
Objectives:
To evaluate the impact of a pharmacist-led primary care review clinic on reducing opioid prescribing.
Methods:
Retrospective analysis of routinely collected opioid prescription data for patients using strong opioids for pain at a practice with high social deprivation and staffed mainly by locum GPs.
Key Findings:
Forty-seven patients were reviewed. The median opioid dose before review was 80 mg oral morphine equivalent. After intervention, the median dose was 30 mg. Thirty-seven (78.7%) patients had reduced doses or discontinued opioids. No adverse events were reported.
Conclusions:
A pharmacist-led clinic aimed at reducing opioid medication appears feasible and effective.
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