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An Algorithm for Annotation of Trypanosoma cruzi MASP Sequences
Aldana A Cepeda Dean1,2, Virginia Balouz3,4, Carlos Andrés Buscaglia3,4
1Instituto de Investigaciones Biotecnológicas (IIBIO), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. acepedadean@iib.unsam.edu.ar.
Methods in Molecular Biology (Clifton, N.J.)
|November 3, 2025
Abstract:
A bioinformatic protocol was developed for the accurate identification, classification, and annotation of mucin-associated surface proteins (MASP) in T. cruzi. This pipeline relies on the screening of molecular signatures in input sequences and can be applied directly to crude parasite genome assemblies, thereby circumventing annotation issues.

