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Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
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Updated: Jan 12, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
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Neighborhood Disadvantage Predicts Surgical Approach in Craniosynostosis Repair.

Manasa H Kalluri1, Aidan W O'Shea1, Daniel Y Chu1

  • 1Division of Plastic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

The Cleft Palate-Craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
|November 3, 2025
PubMed
Summary

Patients from socioeconomically disadvantaged neighborhoods had delayed diagnosis and surgery for craniosynostosis. They were also more likely to undergo open surgery, highlighting disparities in minimally invasive surgical access.

Keywords:
area deprivation indexcranial vault remodelingcraniosynostosisendoscopic strip craniectomyminimally invasive surgerysocial determinants of healthspring-assisted cranioplasty

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Area of Science:

  • Pediatric Surgery
  • Health Services Research
  • Socioeconomic Determinants of Health

Background:

  • Craniosynostosis requires timely surgical intervention.
  • Socioeconomic factors may influence healthcare access and outcomes.

Purpose of the Study:

  • To investigate the association between neighborhood socioeconomic disadvantage and craniosynostosis treatment.
  • To assess differences in diagnosis age, surgery age, and surgical approach based on area deprivation index (ADI).

Main Methods:

  • Retrospective cohort study of 124 patients undergoing primary craniosynostosis repair (2010-2023).
  • Area Deprivation Index (ADI) quintiles were used to assess neighborhood socioeconomic disadvantage.
  • Analysis of age at diagnosis, age at surgery, time to surgery, and operative approach (minimally invasive vs. open).

Main Results:

  • Higher ADI was linked to older age at diagnosis (P=.003) and surgery (P=.001).
  • Increased time from presentation to surgery was observed in higher ADI quintiles (P=.046).
  • Patients from higher ADI quintiles had increased odds of undergoing open surgery (OR 1.516, P=.034) after adjusting for age.

Conclusions:

  • Neighborhood socioeconomic disadvantage is associated with delayed diagnosis and surgery for craniosynostosis.
  • Disparities exist in the utilization of minimally invasive surgery for craniosynostosis repair.
  • Targeted outreach and advocacy are needed to ensure equitable access to timely and appropriate surgical care.