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Non-pharmacologic techniques for interval intrauterine device placement: a systematic review
Tesfaye Tufa1, Emily Snyder2, Sophia Garbarino3
1Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada tesfayehurisa50@gmail.com.
BMJ Sexual & Reproductive Health
|November 3, 2025
Summary
Non-pharmacologic techniques like the Valsalva maneuver and acupuncture may reduce pain during intrauterine device (IUD) placement. However, current evidence is limited, necessitating further high-quality research on IUD insertion pain management.
Area of Science:
- Reproductive Health
- Medical Interventions
- Pain Management
Background:
- Intrauterine devices (IUDs) are effective contraceptives.
- IUD insertion can cause pain, impacting patient experience and uptake.
- Non-pharmacologic techniques are explored as alternatives to manage insertion pain.
Purpose of the Study:
- To systematically review evidence on non-pharmacologic techniques for interval IUD placement.
- To assess the effectiveness of these techniques in reducing pain and improving ease of placement.
Main Methods:
- Searched databases for randomized controlled trials (RCTs) up to December 2023.
- Included RCTs comparing non-pharmacologic techniques to placebo or pharmacologic methods.
- Extracted data on pain, ease of placement, success rates, satisfaction, and adverse events.
Main Results:
- Eleven RCTs evaluated 10 non-pharmacologic techniques; most trials had high risk of bias.
- Valsalva maneuver and acupuncture showed potential for reduced pain during IUD insertion.
- No significant differences were found in ease of placement, success rates, or patient satisfaction.
Conclusions:
- Non-pharmacologic methods like Valsalva maneuver and acupuncture may alleviate IUD insertion pain.
- Evidence quality is moderate to low, with limited sample sizes.
- High-quality trials are needed to confirm effectiveness and guide clinical practice.
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