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Related Experiment Video

Updated: Jan 12, 2026

An Experimental Protocol for Femtosecond NIR/UV - XUV Pump-Probe Experiments with Free-Electron Lasers

An Experimental Protocol for Femtosecond NIR/UV - XUV Pump-Probe Experiments with Free-Electron Lasers

Published on: October 23, 2018

Self-referencing ultrafast wide-field pump-probe microscopy.

Rihan Wu¹, Yaqing Zhang¹, Md Shahjahan¹

¹Department of Chemistry, Michigan State University, East Lansing, MI, USA.

Nature Communications

|November 3, 2025

Summary

We developed a wide-field ultrafast pump-probe microscopy technique to rapidly map material properties. This method significantly reduces noise, enabling faster and more detailed studies of dynamic processes in materials.

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Area of Science:

Materials Science
Spectroscopy
Ultrafast Dynamics

Background:

Ultrafast pump-probe microscopy is crucial for studying material properties like charge and energy transfer.
Current methods are limited by slow scanning speeds and noise, hindering the study of dynamic or photodamage-prone processes.

Purpose of the Study:

To introduce a novel wide-field pump-probe approach to overcome the limitations of point-scanning techniques.
To enable high-throughput material analysis and study of non-repeatable ultrafast phenomena.

Main Methods:

Integration of Parallel Rapid Imaging with Spectroscopic Mapping (PRISM) with a self-referencing denoising technique.
Exploitation of spatial correlations for noise suppression and laser intensity fluctuation mitigation.
Acquisition of over one million pump-probe traces in under a second without a reference detector.

Main Results:

Achieved noise suppression exceeding two orders of magnitude.
Enabled rapid, wide-field acquisition of ultrafast spectroscopic data.
Resolved previously obscured vibrational modes and substrate-induced coupling in WSe₂ and WSe₂/MoSe₂ heterostructures.

Conclusions:

The developed wide-field technique significantly enhances the speed and sensitivity of ultrafast pump-probe microscopy.
This method opens new avenues for high-throughput material screening and real-time investigation of dynamic processes.