Site-specific ligase-dependent conjugation with ring-opening linker improves safety and stability of HER2-targeting

Lei Huang1, Gang Qin2,3, Chengcheng Gong4

  • 1National Key Laboratory of Immunity and Inflammation, National Clinical Research Center for Digestive Diseases, Changhai Clinical Research Unit, Department of Gastroenterology, The First Affiliated Hospital of Naval Medical University/Changhai Hospital, Naval Medical University, 168 Changhai Road, Shanghai, China.

Nature Communications
|November 3, 2025
PubMed

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