Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Equilibrium and Balance01:15

Equilibrium and Balance

6.2K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
6.2K
The Vestibular System01:29

The Vestibular System

43.3K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
43.3K
Hypoxia01:23

Hypoxia

1.9K
Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
1.9K
Hyperpnea and Hyperventilation01:25

Hyperpnea and Hyperventilation

2.4K
Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
2.4K
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

1.0K
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.0K
Physiological Control of Respiration01:23

Physiological Control of Respiration

5.8K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
5.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Moving MRI: Imaging a moving body with a moving magnet.

ArXiv·2026
Same author

Earth Vertical Motions Disrupt Sleep and Next Day Performance.

Nature and science of sleep·2026
Same author

Two-segment aging of vestibular perceptual thresholds: motion-specific links to quiet-stance postural sway.

Frontiers in neurology·2026
Same author

Objective assessment of long-term impact of COVID-19 on multiple sensory functions.

BMC medicine·2026
Same author

The effect of long-term specialized motor experience of the lower limbs on the moving rubber foot illusion.

Psychological research·2025
Same author

Translation and Tilt Perceptual Thresholds Are Elevated in Meniere's Disease Compared With Vestibular Migraine.

Ear and hearing·2025
Same journal

Turbulent flow in a vortex separator with a directed pipe inlet.

Scientific reports·2026
Same journal

Systematic characteristic evaluation of clay-based cementitious material derived from calcium carbide residue and waste tile powder.

Scientific reports·2026
Same journal

Retraction Note: Improvement of a rapid diagnostic application of monoclonal antibodies against avian influenza H7 subtype virus using Europium nanoparticles.

Scientific reports·2026
Same journal

Applying large language models to spam detection in the Kazakh low-resource language setting.

Scientific reports·2026
Same journal

An open-source 3D printing system enabling in-situ freeze-thaw processing of hydrogels.

Scientific reports·2026
Same journal

An enhanced EfficientNet framework for automated waste classification using cosine annealing and label smoothing.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Jan 12, 2026

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
05:02

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Published on: August 30, 2019

7.7K

Mild hypoxia adversely impacts human vestibular function.

Max A Teaford1,2,3, Kyle A Kainec4,5, Kyle A Pettijohn5

  • 1Department of Psychology, University of Tennessee at Chattanooga, Chattanooga, TN, USA. max-teaford@utc.edu.

Scientific Reports
|November 3, 2025
PubMed
Summary
This summary is machine-generated.

Mild hypoxia, like that experienced at 2400m, significantly impairs human vestibular function. This study shows increased vestibular thresholds, suggesting the vestibular system signals the onset of hypoxia.

More Related Videos

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
06:31

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Published on: August 4, 2022

3.6K
Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane
07:24

Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane

Published on: August 22, 2025

468

Related Experiment Videos

Last Updated: Jan 12, 2026

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
05:02

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction

Published on: August 30, 2019

7.7K
Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
06:31

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform

Published on: August 4, 2022

3.6K
Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane
07:24

Using Eye-tracking to Assess the Relative Importance of Visual and Vestibular Input to Subcortical Motion Processing in the Roll Plane

Published on: August 22, 2025

468

Area of Science:

  • Aerospace Medicine
  • Human Physiology
  • Neuroscience

Background:

  • Hypoxia above 3000m adversely affects sensory function.
  • Limited research exists on hypoxia's impact on vestibular function below 2400m.
  • The vestibular system's high metabolic needs suggest vulnerability to hypoxia.

Purpose of the Study:

  • To investigate the impact of mild hypoxia on human vestibular thresholds.
  • To assess vestibular function at simulated altitudes of 2400m (8000 ft).
  • To determine if vestibular changes correlate with arterial oxygen saturation (SpO2).

Main Methods:

  • Participants breathed air with 15.4% O2 to simulate 2400m altitude.
  • Measured earth-vertical translation thresholds.
  • Monitored arterial oxygen saturation (SpO2).

Main Results:

  • Average vestibular thresholds increased by over 20% under hypoxic conditions.
  • Threshold changes negatively correlated with SpO2.
  • Mild hypoxia significantly impacts vestibular function.

Conclusions:

  • Vestibular system changes may serve as an early indicator of hypoxia.
  • Findings highlight the importance of vestibular function in mild hypoxic environments.
  • Further research is needed on vestibular adaptation to altitude.