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Updated: Jun 14, 2026

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Non-invasive Resonance Raman Spectroscopy provides an early estimation of depth in a pig model of multi-depth burns

Rohil Jain1,2, Yanis Berkane1,2,3,4, Emmanuella O Ajenu1,2

  • 1Center for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

Journal of Translational Medicine
|November 4, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Diagnosis of burn depthPig model of burnsRaman spectroscopy

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Raman Spectroscopy: Overview01:20

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The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and the...