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Therapeutic Adherence in Moroccan Hypertensive Patients: Influence of Socioeconomic Status and Fixed-Dose Combination

Yasmine Ouaddouh1,2, Zakaria Bazid1,2,3, Nabila Ismaili1,2,3

  • 1Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.

Current Hypertension Reviews
|November 4, 2025
PubMed

Insights

Patient adherence to hypertension treatment is poor, impacting health outcomes. Strategies like patient education and fixed-dose combination therapies are crucial for improving medication adherence and managing high blood pressure.

Area of Science:

  • Cardiology
  • Public Health
  • Pharmacology

Background:

  • Hypertension is a significant global health concern.
  • Effective management relies on lifestyle changes and medication.
  • Suboptimal patient adherence hinders treatment success due to various factors.

Purpose of the Study:

  • To evaluate adherence to lifestyle modifications and pharmacotherapy in hypertensive patients.
  • To identify factors associated with non-adherence to hypertension management.

Main Methods:

  • A cross-sectional study involving 200 hypertensive patients.
  • Assessed lifestyle adherence via questionnaires, including salt intake, DASH diet, and physical activity.
  • Utilized the Morisky Medication Adherence Scale (MMAS-4) for medication adherence assessment.

Main Results:

  • Overall adherence to lifestyle modifications was 39.8%.
  • Medication adherence was poor in 58.3% of patients.
  • Poor medication adherence linked to older age, lower socioeconomic status, and free-dose combination therapy.

Conclusions:

  • Suboptimal adherence significantly compromises hypertension control.
  • Patient education and fixed-dose combination therapies show potential for improving outcomes.
  • Further multicenter research is needed due to population and healthcare context variability.
Abstract

Keywords:
Hypertensioncardiovascular diseasefixed dose combination therapyhigh blood pressuremorisky medication adherence scale 4.therapeutic adherence

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