Research Status and Hot Spot Visualization Analysis of Osteoporosis from 2014 to 2025

Osteoporosis is a progressive bone condition characterized by the erosion of bone mineral density and weakening of bones. A vast volume of clinical research experimental data on osteoporosis has been published in the last 12 years. These studies are mainly focused on clinical observations, animal experiments, and investigations into pathways and targets. However, this information remains disjointed with scarce systematic reviews and comprehensive analyses.

The Web of Science Core Collection (WoSCC) and PubMed databases were utilized to retrieve relevant osteoporosis literature. Publication volume, journal, authors, keywords, countries, and institutions were bibliometrically and visually analyzed using Citespace 6.3.R3 software, Microsoft Excel 2019, and VOSviewer 1.6.18.0.

There have been 10,343 published reviews and research articles on osteoporosis by 45,966 researchers from 9,462 institutions across 102 countries or regions. Annual publications have been on the rise, particularly in the last few years. The United States, Japan, and China are among the nations involved in this research area. Guangzhou University of Chinese Medicine, and Soochow University are prominent research institutions. Osteoporosis International journal had the most publications and the most cited. Cooper Cyrus was the leading author with a significant volume of publications, while Kanis Ja was noted for having a substantial number of co-citations. An analysis of keywords showed that bone-mineral density, postmenopausal women, and fracture had higher frequencies, leading to thirteen clusters.

Recent research hotspots in osteoporosis are centered on accurate diagnosis, understanding the disease's pathogenesis, and developing effective, scientific prevention and treatment strategies.