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Draft genome sequence of Clostridium tetanomorphum DSM 4474T isolated from a septic wound

Ally Watkins1, Charles Walker Cano1, Emma Hoover1

  • 1Department of Biological Sciences, California State University, Stanislaus, Turlock, California, USA.

Microbiology Resource Announcements
|November 4, 2025
PubMed

Insights

The genome of Clostridium tetanomorphum was sequenced, revealing its potential as a human pathogen and for biofuel production. This bacterium synthesizes butanol without acetone, offering a promising avenue for sustainable energy.

Area of Science:

  • Microbiology
  • Genomics
  • Biotechnology

Background:

  • Clostridium tetanomorphum is an anaerobic bacterium.
  • Its pathogenic potential and industrial applications are of interest.

Purpose of the Study:

  • To sequence the genome of Clostridium tetanomorphum DSM 4474.
  • To identify genes related to pathogenicity and biofuel production.

Main Methods:

  • Whole-genome sequencing of Clostridium tetanomorphum DSM 4474.

Main Results:

  • The complete genome sequence of Clostridium tetanomorphum DSM 4474 was determined.
  • The genome size is 4,374,054 bp.
  • The bacterium synthesizes butanol without acetone byproduct.

Conclusions:

  • The genome sequence provides insights into the biology of Clostridium tetanomorphum.
  • This species holds potential as a human pathogen and for industrial butanol production.
Keywords:
Clostridiumbutanolopportunistic infections

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