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Transglutaminase 2 in chronic inflammation and fibrosis - a potential novel therapy for stricturing Crohn's disease

Jyotsna Chandra1, Gail A West1, Yan Wang1

  • 1Department of Inflammation and Immunity, Cleveland Clinic Research, Cleveland Clinic Foundation, Cleveland, OH, USA.

Expert Review of Clinical Immunology
|November 4, 2025
PubMed
Abstract

Keywords:
Crohn’s diseaseIBDIntestinal fibrosisTransglutaminase2anti-fibrotic therapyextracellular matrixstricturing Crohn’s disease

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