Related Experiment Video
Updated: May 5, 2026

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
Published on: December 4, 2021
Bioactive secondary metabolites from an endophytic fungus Chloridium virescens GLQ05 and structural revision of
Shan Liu1, Pei-Ting Li1, Peishan Li1
1College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Abstract:
Two previously undescribed metabolites, chlovirescenols A (1) and B (5), along with six known compounds including amides (2-4), macrolides (6 and 8), meroterpenoid (7), were obtained from the Ganoderma lucidum-derived endophyte Chloridium virescens GLQ05. Their structural elucidation was achieved through comprehensive spectroscopic analysis. Besides, the originally proposed structure of alteamide has been revised. In the LPS-stimulated RAW264.7 macrophage model, chlovirescenols A (1) and B (5) significantly suppressed the expression of the TNF-α as quantified with RT-qPCR analysis.
Related Concept Videos
Preparation of 1° Amines: Hofmann and Curtius Rearrangement Overview
Drug Metabolism: Phase II Reactions
Production of Antibiotics
iChip
Antifungal Agents

