Prevalence and determinants of anemia among HIV-positive children in central Uganda: A cross sectional study
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View abstract on PubMed
Summary
This summary is machine-generated.Anemia affects over half of HIV-positive children in Uganda, with iron deficiency being a major cause. Malnutrition and advanced HIV stages are key risk factors for anemia in these children.
Area Of Science
- Pediatrics
- Public Health
- Infectious Diseases
Background
- Anemia is a significant public health concern, particularly in resource-limited settings.
- HIV-positive children face severe consequences from anemia.
- Research on anemia in HIV-positive children in low-income countries is limited.
Purpose Of The Study
- To determine the prevalence of anemia among HIV-positive children at Kayunga Regional Referral Hospital.
- To identify factors associated with anemia in this population.
- To assess the proportion of iron deficiency anemia using the Mentzer index.
Main Methods
- A hospital-based cross-sectional study was conducted with 384 HIV-positive children (6 months to 12 years).
- Data collected via questionnaires and medical records included sociodemographic, medical, and laboratory information.
- Anemia and iron deficiency anemia were defined using standard hemoglobin thresholds and the Mentzer index, respectively; logistic regression identified associated factors.
Main Results
- The prevalence of anemia was 57.3% among the studied children.
- Moderate anemia was the most common severity.
- Factors independently associated with anemia included lower caretaker education, more siblings, advanced HIV stages (2 or 3), recent hospital admission, and severe stunting/wasting.
Conclusions
- Anemia is highly prevalent in HIV-positive children in this Ugandan setting.
- Malnutrition and advanced HIV disease are significant risk factors.
- Iron deficiency anemia constitutes a substantial proportion of anemia cases.
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