[Generalized pustular psoriasis: a rare entity in pediatrics]

Generalized pustular psoriasis is a rare and severe systemic inflammatory disease characterized by skin erythema and visible sterile pustules. Associated with hereditary and external factors, it can be life-threatening and requires specialized diagnosis and treatment.

A 6-year-old male with disseminated dermatosis of 7 months evolution, initially appearing in the retroauricular region with erythematous scaly plaques and pustular lesions, spreading to various body segments, accompanied by intense pruritus, fever, and tachycardia. Histopathological examination reported psoriasiform dermatitis with lymphocytes, plasma cell aggregates, and neutrophils forming microabscesses in the stratum corneum, compatible with a diagnosis of pustular psoriasis. Treatment included methotrexate at 12 mg/m²/week, folic acid, 1% methylprednisolone aceponate cream, 0.005% calcipotriol, urea-based emollient at 10%, and antihistamines.

Generalized pustular psoriasis in pediatrics requires comprehensive care, considering not only dermatological aspects but also psychosocial factors. Successful management of pediatric cases, as described, highlights the importance of a personalized approach tailored to each patient's needs to achieve long-term satisfactory outcomes.