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Retrograde Labeling of Retinal Ganglion Cells in Adult Zebrafish with Fluorescent Dyes
Published on: May 3, 2014
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Neuroscience: Retinal information flow governs visual behavior in zebrafish
Gokul Rajan1, Michael B Orger1
1Champalimaud Neuroscience Programme, Champalimaud Foundation, Lisbon 1400-038, Portugal.
Current Biology : CB
|November 4, 2025
Abstract:
Animals adapt their behavior to changing environments by modulating neural circuits at multiple levels. A new study shows that changes in retinal information flow observed at the synaptic level can shape how zebrafish swim in response to visual stimuli.
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Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.

