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Pleural empyema due to polymicrobial Clostridioides difficile, Clostridium tertium and Robinsoniella peoriensis

Edward Lovering1, Obaid Haque1, Marcos Wolff2

  • 1Internal Medicine, MedStar Georgetown University Internal Medicine, Baltimore, USA.

Anaerobe
|November 4, 2025
PubMed

Insights

This case study details a rare polymicrobial empyema caused by Clostridioides difficile, Clostridium tertium, and Robinsoniella peoriensis. It highlights challenges in treating uncommon anaerobic infections, especially with Robinsoniella peoriensis empyema.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Microbiology

Background:

  • Pleural effusion is a common clinical finding, often associated with infections.
  • Clostridioides difficile is a well-known pathogen, but its role in empyema is rare.
  • Polymicrobial anaerobic infections present diagnostic and therapeutic challenges.
Keywords:
Case reportClostridioides difficileEmpyemaRobinsoniella peoriensis

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