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Prochirality

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The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...

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Related Experiment Video

Updated: Jan 12, 2026

A Micropatterning Assay for Measuring Cell Chirality

A Micropatterning Assay for Measuring Cell Chirality

Published on: March 11, 2022

Chirality-Induced Spin Selectivity in Two-Dimensional Self-Assembled Molecular Networks.

Shammi Rana^1,2, Massimiliano Remigio^1,2,3, Lekshmi Aravindan Geetha^1,2

¹Division of Molecular Imaging and Photonics, Department of Chemistry, KU Leuven, Leuven 3001, Belgium.

Journal of the American Chemical Society

|November 4, 2025

Summary

This summary is machine-generated.

Chirality-induced spin selectivity (CISS) was observed in 2D molecular networks. This effect, seen in nonhelical systems, shows potential for spintronic applications.

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Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

Area of Science:

Condensed Matter Physics
Materials Science
Organic Electronics

Background:

Chirality-induced spin selectivity (CISS) is a phenomenon observed in chiral molecules, leading to spin-polarized electron transport.
Previous studies primarily focused on helical systems, limiting the scope of CISS applications.
Exploring CISS in two-dimensional (2D) systems could reveal new physical phenomena and technological possibilities.

Purpose of the Study:

To investigate spin-selective electron transport in 2D self-assembled molecular networks (SAMNs) formed by an enantiopure organic semiconductor.
To explore the operation of the CISS effect in nonhelical, 2D systems.
To assess the potential for spintronic applications using CISS in 2D molecular systems.

Main Methods:

Fabrication of 2D SAMNs using an enantiopure organic semiconductor (dinaphtho[2,3-b:2',3'-f]thieno[3,2-b]thiophene, DNTT) with chiral side chains on a magnetic substrate.
Utilized scanning tunneling microscopy (STM) to visualize molecular arrangements on ferromagnetic surfaces.
Employed scanning tunneling spectroscopy (STS) to measure spin-dependent electron transport and quantify enantiospecific magnetic conductance asymmetry (EMA).

Main Results:

Direct visualization of molecular ordering in 2D SAMNs on ferromagnetic surfaces using STM.
Demonstrated spin-dependent electron transport through 2D SAMNs, confirming the CISS effect.
Observed a significant enantiospecific magnetic conductance asymmetry (EMA) exceeding 40% at room temperature, dependent on molecular enantiomer and substrate magnetization.

Conclusions:

The CISS effect is operative in nonhelical, 2D systems where chirality is expressed in the plane.
2D SAMNs of chiral organic semiconductors provide a novel platform for observing and utilizing CISS.
These findings open new avenues for fundamental research and the development of advanced spintronic devices.