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Assessing medication discrepancies in pediatric patients: a cross-sectional feasibility study using the Medication

Berre Mercümek1,2, Muhammed Yunus Bektay3,4, Selcuk Uzuner5

  • 1Department of Clinical Pharmacy, Institute of Health Sciences, Bezmialem Vakif University, Istanbul, Turkey. berre.mercumek@hotmail.com.

BMC Pediatrics
|November 4, 2025
PubMed

Insights

Medication reconciliation in pediatric transitions of care is improved by the Medication Discrepancy Taxonomy (MedTax). While feasible, MedTax needs refinement for pediatric complexities.

Area of Science:

  • Pediatric Pharmacology
  • Patient Safety
  • Health Informatics

Background:

  • Medication reconciliation (MedRec) is critical during transitions of care (ToC) to prevent errors.
  • Standardized tools for classifying medication discrepancies are inconsistently applied in pediatrics.
  • The Medication Discrepancy Taxonomy (MedTax) offers a potential solution for pediatric MedRec.

Purpose of the Study:

  • To assess the feasibility of the Medication Discrepancy Taxonomy (MedTax) for identifying and classifying medication discrepancies in pediatric patients during ToC.
  • To evaluate the effectiveness of MedTax in a real-world pediatric setting.
  • To identify areas for improvement in MedTax for pediatric application.

Main Methods:

  • Prospective cross-sectional study of pediatric patients hospitalized between August 2022 and February 2023.
  • Pharmacist-led MedRec during admissions and transfers.
  • Classification of discrepancies using MedTax for unintentional errors.

Main Results:

  • 105 pediatric patients included, with a mean of 8.35 medications per patient.
  • 518 medication discrepancies identified; 9.1% were unintentional.
  • MedTax classified all discrepancies, but 6.38% presented categorization challenges.

Conclusions:

  • The MedTax taxonomy is feasible for identifying and classifying pediatric medication discrepancies during ToC.
  • Refinement of MedTax is necessary to address pediatric-specific medication complexities.
  • Developing tailored tools is crucial for enhancing pediatric medication reconciliation.
Abstract

Keywords:
MedTaxMedication discrepanciesMedication reconciliationPatient safetyPediatricTransitions of care

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