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Improving Beta-Lactam Allergy Risk Stratification Through Digital Decision Support: A Randomized Crossover Study of

Man Yui Chong1,2, Weihong Shi1,2, Maja Bulatović-Ćalasan3,4

  • 1Division of Rheumatology & Clinical Immunology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China.

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PubMed
Abstract

No abstract available in PubMed .

Keywords:
APAAACIBLAST‐Aallergybeta‐lactamdelabelingpenicillin

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Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

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