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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Articles linked to this work by shared authors, journal, and citation graph.

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In Situ Fenestration With the Electrified Wire Technique-Exploring the Role of Application Duration on Fenestration Size: A Case Report.

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Related Experiment Video

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The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
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Physician-Modified Custom Made Endograft Adding an Outer Branch to Correct a Fenestration Offset.

Lorenzo Torri1, Petroula Nana1, José I Torrealba1

  • 1German Aortic Center, Department of Vascular Medicine, University Heart and Vascular Centre UKE Hamburg, Hamburg, Germany.

Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists
|November 5, 2025
PubMed
Summary

This study demonstrates a physician-modified endograft (PMEG) technique using an outer branch in a custom-made device (CMD) for urgent juxtarenal aneurysm repair. This adaptable approach successfully treated a complex case, highlighting its utility in time-sensitive situations.

Keywords:
endovascular aortic repairphysician-modified endograftruptured abdominal aortic aneurysmsymptomatic abdominal aortic aneurysm

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Area of Science:

  • Vascular Surgery
  • Endovascular Aneurysm Repair
  • Aortic Aneurysm Management

Background:

  • Juxtarenal aortic aneurysms present complex endovascular repair challenges.
  • Custom-made devices (CMDs) offer tailored solutions but require significant lead time.
  • Urgent cases may necessitate rapid adaptation of available endovascular devices.

Purpose of the Study:

  • To describe a novel physician-modified endograft (PMEG) technique.
  • To incorporate an outer branch into a pre-existing fenestrated CMD for urgent juxtarenal aneurysm repair.
  • To manage a complex aortic anatomy when a standard device was not immediately available.

Main Methods:

  • An 80-year-old male with an 80 mm juxtarenal aneurysm underwent urgent repair.
  • A fenestrated CMD intended for another patient was utilized.
  • A retrograde outer branch was created by suturing a covered stent to a misaligned fenestration.

Main Results:

  • The PMEG procedure was technically successful.
  • The postoperative course was uneventful.
  • Predischarge imaging confirmed target vessel patency and absence of endoleak.

Conclusions:

  • Physician modification of CMDs, including adding outer branches, is feasible for urgent complex aortic aneurysm repair.
  • Utilizing available CMDs reduces preparation time and complexity in emergent scenarios.
  • This technique expands the applicability of fenestrated stent grafts in situations lacking off-the-shelf options.