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Updated: Jun 27, 2026

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
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Is There a Role for Sodium Fluoride in Otosclerosis Treatment?
Timothy Shim1, Kevin Wong1, Michael J Ruckenstein1
1Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Abstract:
Various reports have investigated the role of NaF for stabilizing SNHL in the setting of otosclerosis; however, there currently remains no established practice guideline or widespread consensus. The purpose of this paper is to interpret the literature to determine best practices for the use of NaF in otosclerosis management.
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