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Updated: Jan 12, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Hospital Variations in Time-To-Crisis-Resolution Among Children and Adolescents With Sickle Cell Disease.
Chris A Rees1,2, Dunia Hatabah1, Rawan Korman1
1Department of Pediatrics, Division of Pediatric Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Patient factors and hospital location significantly impact pain management and recovery for children with sickle cell disease. Future studies must consider these variables for effective clinical trial design.
Area of Science:
- Pediatric Hematology
- Clinical Trial Design
- Pain Management
Background:
- Sickle cell disease (SCD) is a genetic blood disorder causing severe pain crises.
- Opioid analgesics are commonly used for pain management in SCD.
- Variability in treatment outcomes necessitates understanding influencing factors.
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