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Updated: Jan 12, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Hospital Variations in Time-To-Crisis-Resolution Among Children and Adolescents With Sickle Cell Disease
Chris A Rees1,2, Dunia Hatabah1, Rawan Korman1
1Department of Pediatrics, Division of Pediatric Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Abstract:
Analysis of the placebo cohort in the STArT trial shows that patient characteristics and hospital site strongly influence time-to-crisis-resolution and total opioid use in children and young adults with sickle cell disease, highlighting the need to account for these factors in the design of future clinical trials.
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